Approximately 25% of women who are experiencing infertility have medical issues related to ovulation. These include failure to release an egg (anovulation) or an inability to develop and mature a healthy egg. Some conditions associated with ovulation dysfunction are polycystic ovarian syndrome (PCOS), thyroid issues, and irregular or absent menstrual cycles (amenorrhea).
Medication can be prescribed to induce ovulation and improve the lining of the uterus (endometrium). These drugs simulate follicle stimulation hormone (FSH) and luteinizing hormone (LH), which are normally produced by the pituitary gland to develop ovarian follicles and trigger ovulation. The drugs may be administered orally or as injections. Some of these medications include Clomiphene Citrate (Clomid), Glucophage (Metformin), Letrozole (Femara), Menotropins (Menopur), Gonal-F (Gonadotripin), and Urofollitropin (Follistim).
Ovulation induction may also be used in conjunction with IUI, IVF, or other treatments to increase the number of ovarian follicles (where the egg matures) and the potential for the release of multiple mature ova. This can provide a greater chance at fertilization success due to the increased number of released ova. Ovulation induction can also regulate and control the timing of ovulation.
If you are diagnosed with ovulation dysfunction after a hormonal evaluation, our physicians will select the best medication for your specific treatment. For more information on ovulation induction and medication, please read the American Society for Reproductive Medicine guide for patients.