Pre-implantation Genetic Diagnosis and Screening (PGD/PGS) may be recommended during IVF to screen the embryo(s) for certain genetic diseases or chromosomal abnormalities. Once an egg is fertilized and grows into an optimal number of cells, a biopsy of the embryo(s) is performed and cells are removed to be analyzed for potential genetic conditions. This process allows the selection of the healthiest embryo(s) for transfer; selection is also possible based on gender balancing. PGD/PGS may require that the embryo(s) be frozen in order to be transferred at a later time.
PGD is used to test for single gene diseases that are inherited from one or both of the parents. Some of these disorders include Sickle Cell Anemia, Tay Sachs, Cystic Fibrosis, Huntington’s Disease, and others. PGS discovers chromosomal abnormalities that may cause a miscarriage or IVF failure, or a trisomy such as Down Syndrome.
These procedures may be appropriate for patients who are known carriers of genetic diseases, have a history of multiple miscarriages (recurrent pregnancy loss), or have repeated IVF failures with no identifiable causes. PGD/PGS provides valuable knowledge and diagnosis to our doctors and genetic counselors to ensure the proper treatment and care for the patient. We will work with you before and after PGD/PGS to help you make the most informed decision possible.